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Pharmevo Private Limited.

Sacvin Tablets 24mg/26mg

In stock Per Box
Rs 1,234 Rs 1,173 Save Rs 61 (5% off)

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Customer reviews

  • Hina P. 24-Jul-2025 || 02:51 AM

    Fast delivery of sacvin tablets 24mg/26mg to Hyderabad. Packaging was secure and invoice was included.

  • Faisal N. 20-Mar-2026 || 05:25 AM

    Checked sacvin tablets 24mg/26mg with local chemist — said supply looks fine. Relief!

  • Bilal J. 08-Apr-2025 || 12:35 AM

    Needed sacvin tablets 24mg/26mg urgently — team arranged quick dispatch. Product was original MRP labeled.

  • Hassan H. 10-May-2025 || 11:03 PM

    Happy with sacvin tablets 24mg/26mg. Customer team confirmed batch details before dispatch. Professional service.

  • Ahmed Q. 27-Jan-2025 || 08:09 AM

    Excellent communication about sacvin tablets 24mg/26mg availability. No fake “in stock” trap.

  • Sana J. 02-Feb-2026 || 01:42 AM

    Quality of sacvin tablets 24mg/26mg is as expected. Instructions on label were clear. Trustworthy site.

  • Hina A. 29-Aug-2025 || 03:10 AM

    Authentic product. sacvin tablets 24mg/26mg matched the description on the website. Satisfied customer.

  • Noman T. 01-May-2025 || 01:00 AM

    Received sacvin tablets 24mg/26mg in good condition. Tracking updates were accurate. Five stars.

  • Nadia S. 05-Nov-2025 || 09:42 AM

    Good experience with sacvin tablets 24mg/26mg. Price was better than local pharmacy and delivery was on time.

  • Maryam J. 08-Nov-2025 || 09:56 PM

    Value for money on sacvin tablets 24mg/26mg. Discount was applied correctly at checkout.

  • Shahid Q. 05-Apr-2025 || 02:24 AM

    Product sacvin tablets 24mg/26mg works fine for daily use. Delivery to Quetta took 3 business days.

  • Maryam N. 07-Sep-2025 || 08:04 AM

    No complaints about sacvin tablets 24mg/26mg. Would suggest adding more payment options, otherwise great.

  • Rabia J. 23-Jul-2025 || 06:55 AM

    Using sacvin tablets 24mg/26mg as prescribed — no issues with quality. Will order again from MedicinePrices.pk.

  • Omar M. 04-Jan-2026 || 06:03 AM

    Reasonable delivery fee for sacvin tablets 24mg/26mg to Peshawar. Product exactly as shown online.

  • Waqas B. 15-Mar-2026 || 03:51 AM

    Will continue sacvin tablets 24mg/26mg from this store — consistent batches and polite support.

  • Zainab Z. 19-May-2025 || 02:22 AM

    Been ordering sacvin tablets 24mg/26mg monthly. Never received a damaged or near-expiry pack so far.

  • Ayesha A. 22-Mar-2025 || 03:08 AM

    Simple reorder of sacvin tablets 24mg/26mg from order history would be nice — product itself is great.

  • Kamran K. 11-Sep-2025 || 04:55 AM

    Using sacvin tablets 24mg/26mg for two weeks — no side issues from supply. Seems genuine.

  • Maryam Z. 15-Aug-2025 || 03:57 AM

    Recommended sacvin tablets 24mg/26mg to a colleague — they also had a positive experience.

  • Maryam S. 29-Jul-2025 || 04:13 AM

    Using sacvin tablets 24mg/26mg as prescribed — no issues with quality. Will order again from MedicinePrices.pk.

  • Rabia Z. 08-Jan-2025 || 11:46 PM

    Five-star for sacvin tablets 24mg/26mg quality; four-star only because I wanted Sunday delivery.

  • Ayesha T. 08-Aug-2025 || 01:58 AM

    Helpful staff guided me on dosage for sacvin tablets 24mg/26mg. Extra care appreciated.

  • Fatima B. 13-Nov-2025 || 04:09 AM

    Packaging of sacvin tablets 24mg/26mg was discreet and professional. Delivery agent called before arrival.

  • Imran K. 26-Jan-2025 || 07:03 AM

    Asked questions about sacvin tablets 24mg/26mg on WhatsApp — got a clear reply within minutes.

  • Amna H. 05-Jan-2026 || 02:46 AM

    Found sacvin tablets 24mg/26mg after searching many sites. MedicinePrices.pk had real stock.

  • Ali N. 19-May-2025 || 04:59 AM

    Happy that sacvin tablets 24mg/26mg is sourced properly. Feels like a real licensed pharmacy operation.

  • Saad H. 13-May-2026 || 03:41 AM

    Reliable source for sacvin tablets 24mg/26mg in Pakistan. Invoice helped for office reimbursement.

  • Fatima T. 04-May-2025 || 01:39 AM

    Clear product page for sacvin tablets 24mg/26mg helped me compare strength and pack size.

  • Zainab J. 18-Mar-2025 || 04:40 AM

    Ordered sacvin tablets 24mg/26mg for my parents. MedicinePrices.pk verified stock and helpful WhatsApp support.

  • Maryam A. 02-Dec-2025 || 02:26 AM

    Impressed with how sacvin tablets 24mg/26mg was bubble-wrapped. Cold chain not needed but pack was solid.

  • Asad T. 08-Apr-2026 || 08:40 AM

    My pharmacist confirmed sacvin tablets 24mg/26mg looked original. MedicinePrices.pk is now my go-to.

  • Kamran T. 28-Apr-2025 || 03:29 AM

    Good deal on sacvin tablets 24mg/26mg during sale. Still authentic — checked barcode.

  • Kashif M. 31-Jan-2026 || 10:26 PM

    Took sacvin tablets 24mg/26mg as directed — improvement as expected. Thanks for timely supply to Quetta.

  • Sana R. 04-Nov-2025 || 06:21 AM

    First order of sacvin tablets 24mg/26mg went smoothly. COD worked fine and rider was polite.

  • Sana B. 21-Dec-2025 || 02:39 AM

    Bought sacvin tablets 24mg/26mg twice now — consistent quality and reliable courier each time.

  • Laiba H. 13-May-2025 || 07:04 AM

    Minor delay for sacvin tablets 24mg/26mg due to rain in Islamabad, but team kept me updated.

  • Imran S. 28-Feb-2026 || 12:10 AM

    Smooth ordering process for sacvin tablets 24mg/26mg. Email confirmation and dispatch SMS were helpful.

  • Sadia K. 08-Jun-2026 || 10:57 PM

    Satisfied with sacvin tablets 24mg/26mg for home use. Website is easy on mobile too.

  • Kamran J. 20-Mar-2026 || 10:28 PM

    Trust factor is high for sacvin tablets 24mg/26mg here. Proper GST-style receipt provided.

  • Tariq I. 25-Mar-2026 || 03:03 AM

    Good for repeat purchases. sacvin tablets 24mg/26mg stock was available when other sites were out.

  • Ahmed S. 15-Dec-2025 || 10:41 PM

    Fair pricing on sacvin tablets 24mg/26mg compared to other online stores in Pakistan. No hidden charges.

  • Rabia J. 26-Jan-2026 || 01:03 AM

    Bulk-friendly service; I ordered several units of sacvin tablets 24mg/26mg without hassle.

  • Shahid K. 02-Feb-2025 || 10:36 PM

    sacvin tablets 24mg/26mg arrived before the estimated date in Karachi. Legit pharmacy feel, not a random seller.

  • Laiba H. 30-Jan-2026 || 07:43 AM

    Recommended by my doctor; found sacvin tablets 24mg/26mg here at a fair price. Checkout was simple.

  • Ahmed S. 29-Aug-2025 || 06:44 AM

    Quick response when I asked about substitutes for sacvin tablets 24mg/26mg. Good pharmacy ethics.

  • Omar K. 08-Sep-2025 || 06:38 AM

    Ordered sacvin tablets 24mg/26mg with other items — all packed in one box, nothing missing.

  • Maryam N. 14-Jan-2026 || 04:39 AM

    Received correct quantity of sacvin tablets 24mg/26mg. Strip seal was intact. Happy with the purchase.

  • Saad R. 18-Jan-2025 || 07:59 AM

    Second time buying sacvin tablets 24mg/26mg — same quality as first order. Loyal customer now.

  • Maryam Q. 12-Apr-2026 || 05:41 AM

    Good experience overall. sacvin tablets 24mg/26mg price beat the market near Islamabad.

  • Fatima R. 04-Feb-2026 || 06:32 AM

    Genuine sacvin tablets 24mg/26mg — sealed pack and correct expiry. Delivered within 2 days in Multan.

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Description

Sacvin Tablets Specification

Requires Prescription (YES/NO)

Yes

Generics

Sacubitril , Valsartan

Used For

Heart Failure

How it works

Sacubitril + valsartan inhibits neprilysin (neutral endopeptidase; NEP) , the active metabolite of the prodrug sacubitril and blocks the angiotensin II type-1 (AT1) receptor via valsartan. The cardiovascular and renal effects of sacubitril + valsartan in heart failure patients are attributed to the increased levels of peptides that are degraded by neprilysin, such as natriuretic peptides (NPs) and the simultaneous inhibition of the effects of angiotensin II by valsartan. NPs exert their effects by activating membrane bound guanylyl cyclase coupled receptors, resulting in increased concentrations of the second messenger cyclic guanosine monophosphate (cGMP), which could result in vasodilation, natriuresis and diuresis, increased glomerular filtration rate and renal blood flow, inhibition of renin and aldosterone release, reduction ofsympathetic activity and antihypertrophic and antifibrotic effects. Valsartan inhibits the effects of angiotensin II by selectively blocking the AT1 receptor and also inhibits angiotensin II-dependent aldosterone release. This prevents sustained activation of the renin-angiotensin-aldosterone system that would result in vasoconstriction, renal sodium and fluid retention, activation of cellular growth and proliferation and subsequent maladaptive cardiovascular remodeling.

Sacvin Tablets Usage And Safety

Dosage

Sacubitril , Valsartan

Side Effects

Very Common : Hyperkalemia, hypotension and renal impairment.Common : Anemia, hypokalemia, hypoglycemia, dizziness, headache, syncope, vertigo, orthostatic hypotension, cough, diarrhea, nausea, gastritis, renal failure (renal failure, acute renal failure), fatigue and asthenia.Uncommon : Hypersensitivity, dizziness postural, pruritus, rash and angioedema.

Drug Interactions

Angiotensin Receptor Blockers , OATP1B1 and OATP1B3 substrates, e.g. statins , PDE5 inhibitors including sildenafil , potassium-sparing diuretics (triamterene, amiloride), mineralocorticoid antagonists (e.g. spironolactone, eplerenone), potassium supplements, salt substitutes containing potassium or other agents (such as heparin) , Non-steroidal anti-inflammatory agents (NSAIDs), including selective cyclooxygenase-2 (COX-2) inhibitors , Lithium , OATP1B1, OATP1B3, OAT3 (e.g. rifampicin, ciclosporin), OAT1 (e.g. tenofovir, cidofovir) or MRP2 (e.g. ritonavir) , Metformin HCl.

Indication

Sacubitril + Valsartan is indicated in adult patients for treatment of symptomatic chronic heart failure with reduced ejection fraction. Sacubitril + Valsartan is usually administered in conjunction with other heart failure therapies, in place of an ACE inhibitor or other ARB.

When not to Use

Sacubitril + Valsartan is contraindicated in patients with:• Hypersensitivity to the active substance, sacubitril, valsartan or to any of the excipient of the product.• Concomitant use with ACE inhibitors. Sacubitril + Valsartan must not be administered until 36 hours after discontinuing ACE inhibitor therapy.• Known history of angioedema related to previous ACE inhibitor or ARB therapy.• Hereditary or idiopathic angioedema.• Concomitant use with aliskiren-containing medicinal products in patients with diabetes mellitus or in patients with renal impairment (eGFR <60 ml/min/1.73 m2 ).• Severe hepatic impairment, biliary cirrhosis and cholestasis.• Second and third trimester of pregnancy

Sacvin Tablets Precautions

Precaution

Sacubitril + valsartan may cause angioedema. If angioedema occurs, discontinue sacubitril + valsartan immediately, provide appropriate therapy and monitor for airway compromise. Sacubitril + valsartan should not be used in patients with a known history of angioedema related to previous ACE inhibitor or ARB therapy.

Sacvin Tablets Warnings

Warning 1

Sacubitril + valsartan lowers blood pressure and may cause symptomatic hypotension. Patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), are at greater risk. Correct volume or salt depletion prior to administration of sacubitril + valsartan or start at a lower dose. If hypotension occurs, consider dose adjustment of diuretics, concomitant antihypertensive drugs and treatment of other causes of hypotension (e.g., hypovolemia). If hypotension persists despite such measures, reduce the dosage or temporarily discontinue sacubitril + valsartan.

Warning 2

Through its actions on the RAAS, hyperkalemia may occur with sacubitril + valsartan. Monitor serum potassium periodically and treat appropriately, especially in patients with risk factors for hyperkalemia such as severe renal impairment, diabetes, hypoaldosteronism or a high potassium diet. Dosage reduction or interruption of sacubitril + valsartan may be required.

Warning 3

Caution should be exercised when initiating sacubitril + valsartan in patients with NYHA functional classification IV due to limited clinical experience in this population.

Sacvin Tablets Additional Information

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.


Product information
Unit
Per Box
SKU
#99
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